Viability of the acetabular roof in developmental dysplasia of the hip (dislocated) affected by mycoplasmas. Study with early termination

Authors

  • Antonio Redon-Tavera Clínica de Cadera Congénita INR.
  • Hilda Villegas-Castrejón Directora de Investigación y Jefe del Laboratorio de Microscopía Electrónica INR
  • José Antonio Rivera- Tapia Laboratorio de Micoplasmas. Benemérita Universidad Autónoma de Puebla.
  • Saúl Renán León-Hernández División de Investigación y Bioestadística INR.
  • Cristina Velasquillo-Martínez Unidad de Ingeniería de Tejidos INR.

Keywords:

Dysplasia, hip, developmental, congenital, acetabulum, mycoplasmas

Abstract

Objective: Investigate chondral tissue viability invaded by mycoplasma in hip developmental
dysplasia and dislocation. Materials and methods: A triple-blind cohort study of 15 infants,
aged 12 through 36 months, was scheduled to examinate samples of tissue obtained at the
time of the hip reduction surgery, from the anterior wall of acetabulum and from the hip joint
capsule, to perform on electron microscopy, tissue culture and mycoplasmas culture. Results
of each lab were unknown for the others. Results: Only five cases were examined. The early
first three were positive for mycoplasmas, case one by electron microscopy at cartilage and
capsule and two more cases by culture for mycoplasmas. Late reported cases two to five
were also positive by electron microscopy in acetabular cartilage. At the end, all five studied
cases were positive by one test or another. Conclusion: Our former main objective was not

accomplished as a result of interruption in advance, which was carried out to avoid introduc-
tion of mycoplasmas into the tissue lab. However, findings are consistent to the presence of

mycoplasmas in the structures of congenital hips.

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References

Rivera TJA, Cedillo RML, Vega BM. Micoplasmas y su

importancia médica. Rev Biomed 2001; 12 (4): 262-271.

Rivera TJA, Cedillo RML, Giono CL. Comparación ge-

nómica en micoplasmas de interés médico. An Med Am

Britt Cowdray Med Cent México 2006; 51 (2): 74-79.

Redon TA, Villegas CH, Isunza AOD, Rivera TA, León

HSR. Incidental fi nding of Mycoplasmas in develop-

mental dysplasia of the hip and hip dislocation. Sci Res

Essays 2010; 5 (13): 1676-1682.

León HSR, León BS. Teoría del micoplasma como

agente causal necesario de las displasias del desarrollo

de la cadera (DDC). En prensa.

Waites KB, Katz B, Schelonka RB. Mycoplasmas and

ureaplasmas as neonatal pathogens. Clin Microbiol Rev

; 18 (4): 757-789.

Hayfl ick L, Chanock RM. Mycoplasma species of man.

Bacteriol Rev 1965; 29 (2): 185-221.

Dusanic D, Bencina D, Oven I, Cizelj I, Bencina M, Narat

M. Mycoplasma synoviae induces upregulation of apop-

totic genes, secretion nitric oxide and appearance of an

apoptotic phenotype in infected chicken condrocytes.

Vet Res 2012; 43 (7): 1-14.

Kohn DF, Magill LS, Chinookoswong N. Localization of

Mycoplasma pulmonis in cartilage. Infect Immun 1982;

(2): 730-733.

Cabrera TM. Medición de presiones hidrodinámicas en

modelo experimental de aorta fetal. Tesis de Alta Es-

pecialidad. UNAM, Instituto Nacional de Rehabilitación.

México, 2012.

Redon TA. Ortopedia para la práctica médica general.

México. Editorial Trillas, 2a Edición. 2013. En Prensa.

Pacifi ci M. How do synovial joints come about? J Am

Acad Orthop Surg 2008; 16 (10): 616-617.

Published

2026-04-08

How to Cite

1.
Redon-Tavera A, Villegas-Castrejón H, Rivera- Tapia JA, León-Hernández SR, Velasquillo-Martínez C. Viability of the acetabular roof in developmental dysplasia of the hip (dislocated) affected by mycoplasmas. Study with early termination. Invest. Discapacidad [Internet]. 2026 Apr. 8 [cited 2026 Apr. 10];1(2):59-65. Available from: https://dsm.inr.gob.mx/indiscap/index.php/INDISCAP/article/view/953

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