Medical importance of Staphylococcus epidermidis biofilm in joint prosthesis infections
Keywords:
Cerebral palsy, drooling, botulinum toxin type AAbstract
Joint replacement is a surgical procedure performed in patients with articular wear. This surgery
helps them to improve their mobility and quality of life; however, it can cause complications in
some cases. Prosthetic joint infection is the most serious and catastrophic complication that may
occur after a joint replacement procedure. The most common etiologic agent in these infections
is Staphylococcus epidermidis. Prosthetic joint infections that are caused by S. epidermidis are
usually chronic and persistent because these microorganisms are found as a biofilm. This biofilm
is a barrier that protects the bacterial cells from the action of antibiotics and the host’s immune
response. The formation of the biofilm is a complex process that occurs in four phases. Better
understanding of the pathophysiology of infections caused by biofilm-producing microorganisms
can help to find more effective therapeutic strategies.
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