Imaging and etiological correlation in Vertebral Destruction Syndrome
Imaging Correlation in Vertebral Destruction Syndrome: Preliminary Findings from a Retrospective Case Series
Keywords:
Spine, SPINE SURGERY, VERTEBRAL DESTRUCTION SYNDROMEAbstract
Background:
Vertebral Destruction Syndrome (VDS) is a multifactorial spinal disorder with infectious, neoplastic, metabolic, or idiopathic causes, leading to vertebral collapse, instability, and potential neurological deficits. Imaging studies are essential for detecting structural alterations; however, overlapping features among etiologies often delay diagnosis.
Objective:
To correlate imaging findings with the underlying etiology of VDS and identify characteristic radiological patterns that improve diagnostic accuracy.
Methods:
A retrospective case series of 48 patients with VDS (2013–2023) was analyzed through radiographs, CT, and MRI. Imaging variables included vertebral morphology, endplate erosion, disc and paravertebral involvement, and canal compromise. Cramer’s V assessed correlation strength.
Preliminary Results:
Infectious causes predominated (54%), followed by neoplastic (40%) and metabolic (6%). Pyogenic infection (33%) and multiple myeloma (21%) were most common.
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Copyright (c) 2025 Instituto Nacional de Rehabilitación Luis Guillermo Ibarra Ibarra

This work is licensed under a Creative Commons Attribution 4.0 International License.
© Instituto Nacional de Rehabilitación Luis Guillermo Ibarra Ibarra under a Creative Commons Attribution 4.0 International (CC BY 4.0) license which allows to reproduce and modify the content if appropiate recognition to the original source is given.

