Imaging and etiological correlation in Vertebral Destruction Syndrome

Imaging Correlation in Vertebral Destruction Syndrome: Preliminary Findings from a Retrospective Case Series

Authors

  • RODOLFO JOSE MARTINEZ DEL ROSAL RIVERA
  • ARMANDO ALPIZAR AGUIRRE
  • OMAR ESTEVEZ
  • CARLA GARCIA RAMOS
  • ALEJANDRO ANTONIO REYES SANCHEZ
  • BARON ZARATE KALFOPULOS

Keywords:

Spine, SPINE SURGERY, VERTEBRAL DESTRUCTION SYNDROME

Abstract

Background:
Vertebral Destruction Syndrome (VDS) is a multifactorial spinal disorder with infectious, neoplastic, metabolic, or idiopathic causes, leading to vertebral collapse, instability, and potential neurological deficits. Imaging studies are essential for detecting structural alterations; however, overlapping features among etiologies often delay diagnosis.

Objective:
To correlate imaging findings with the underlying etiology of VDS and identify characteristic radiological patterns that improve diagnostic accuracy.

Methods:
A retrospective case series of 48 patients with VDS (2013–2023) was analyzed through radiographs, CT, and MRI. Imaging variables included vertebral morphology, endplate erosion, disc and paravertebral involvement, and canal compromise. Cramer’s V assessed correlation strength.

Preliminary Results:
Infectious causes predominated (54%), followed by neoplastic (40%) and metabolic (6%). Pyogenic infection (33%) and multiple myeloma (21%) were most common.

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Published

2025-11-11

How to Cite

1.
MARTINEZ DEL ROSAL RIVERA RJ, ALPIZAR AGUIRRE A, ESTEVEZ O, GARCIA RAMOS C, REYES SANCHEZ AA, ZARATE KALFOPULOS B. Imaging and etiological correlation in Vertebral Destruction Syndrome: Imaging Correlation in Vertebral Destruction Syndrome: Preliminary Findings from a Retrospective Case Series. Invest. Discapacidad [Internet]. 2025 Nov. 11 [cited 2025 Nov. 19];11(S2). Available from: https://dsm.inr.gob.mx/indiscap/index.php/INDISCAP/article/view/740

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