The role of physical activity on depression in patients with Parkinson´s disease
DOI:
https://doi.org/10.35366/107512Keywords:
parkinson’s disease, depression, physical activity, mental health, basal gangliaAbstract
Depression frequently occurs in patients with Parkinson’s disease (PD), affecting approximately 50%. Currently, the treatment of this disorder is based on the administration of selective serotonin reuptake inhibitors. However, these drugs can often lead to numerous side effects that impair patients’ quality of life. Therefore, it is necessary to identify other effective and safe treatments. There is evidence that practicing physical exercises reduces inflammation, improves cerebral blood flow, increases the production of neurotrophic factors, and increases the volume of brain areas related to memory and cognitive function, improving mood and some mental aspects. Therefore, physical activity can counteract brain alterations associated with neurodegenerative disorders and depression. In this regard, some studies have been conducted to determine whether such exercises can improve mental health in people with PD. In particular, some research groups have proposed resistance training, aerobic exercises, yoga, dance, virtual reality-based approaches, and exergames to reduce depression levels in these patients. Therefore, there is increasing evidence supporting the usefulness of performing physical exercises to treat depression in these patients. This article aims to highlight the therapeutic potential of performing physical activity in managing depression in patients with PD.
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